Working with True Lies – Statistics in Biology

23/02/2016

Meet Fred. This story starts with a hypothetical PhD student. Let’s call him Fred. Fred is doing a PhD in food science and has a vegetarian flat-mate (let’s call her Karen). After living with Karen for a few months, Fred noticed that Karen and her vegetarian friends eat a lot...

Workflow Wednesdays – Coverage analysis 2. and other alignment statistics

02/10/2013

As I promised last week, I’ll show you some command line based alignment analysis tools this week. As there are basically an endless number of methods for generating alignment statistics, feel free to share additional tips and tricks in the comment section!

Workflow Wednesdays – Coverage analysis 1.

25/09/2013

Nowadays, when whole exome and whole genome alignments are becoming fairly routine and even gene panels often target hundreds of genes, it’s no longer a valid option for researchers to visually check the quality of alignments. Generating coverage measures and statistics is a good tool for identifying sequencing or alignment...

Bioinformatics for Beginners – R

19/08/2013

No, today is not Talk Like A Pirate Day. “R” is a statistical software (more like an environment) which was inspired by “S” and was originally developed by Robert Gentleman and Ross Ihaka. Nowadays, more than a dozen contributors are working on development and bug fixes. There are also more...